The SEARCH-CC was a case-control project conducted from 2003 to 2006 that studied 10-22 year old children and adolescents with or without diabetes, focusing on type 2 diabetes in youth and drawing upon the CDC funded SEARCH diabetes project in Colorado and South Carolina. The SEARCH project ascertained cases of diabetes in youth, collected immunologic, clinical, and metabolic information, and classified cases as type 1, type 2 or other types (hybrids) of diabetes. SEARCH-CC recruited appropriate controls aged 10-22 years from three ethnic backgrounds including African Americans (AA), Hispanics (H), and non-Hispanic whites (NHW). SEARCH-CC added selected measurements not available in SEARCH to explore or describe:
- Specific etiologic hypotheses in the cases classified by SEARCH as type 2 diabetes.
- Cardiovascular risk factor differences in youth with diabetes and non-diabetic controls.
- Among controls, insulin resistance and secretion differences according to levels of the same risk factors under study.
- Among youth with diabetes, the relationship between depression and diabetes management, quality of life, and self-concept.
- Among youth with and without diabetes, the relationship between diabetes and depression and related psychosocial factors.
For more information, contact Ralph B. D'Agostino, Jr., PhD at firstname.lastname@example.org