Dr. D'Agostino's primary area of statistical research involves developing methods for using propensity scores in medical research. He has published extensively in this area and has presented many lectures and workshops in this topic. In addition to this research, Dr. D’Agostino is the Director of the Biostatistics Core for the Wake Forest School of Medicine Comprehensive Cancer Center and the Co-Director of the CDC funded SEARCH (Search for Diabetes in Youth) Data Coordinating Center. He has also been the Principal Investigator on seven other RO1-grants/subcontracts funded by NIH as well as being the lead statistician on numerous other NIH and Foundation funded research projects.
Dr. D'Agostino has published over 185 manuscripts and book chapters in areas of statistical methodology, cardiovascular disease, diabetes, cancer and genetics. He has extensive experience in the design and analysis of clinical trials, observational studies and large scale epidemiologic studies including the Insulin Resistance Atherosclerosis Study (IRAS), Subclinical Cardiovascular Disease Study (MESA) and the Search for Diabetes in Youth Study (SEARCH).
Lynne E. Wagenknecht, DrPH, Associate Dean for Interdisciplinary Research, is Professor and Associate Director of Public Health Sciences. She is an epidemiologist with an active portfolio of both clinical trials and observational epidemiologic studies in the areas of cardiovascular disease, diabetes, and obesity. She has a particular interest in study design and implementation of clinical trials. She is the Associate Director of the Research Expertise and Methods program of the Wake Forest Clinical and Translational Science Institute. She is a multiple PI on the Look AHEAD Trial Coordinating Center, which is examining the impact of a behavioral lifestyle intervention on risk of multiple outcomes in obese type 2 diabetics. She also leads the Wake Forest sites of the Atherosclerosis Risk in Communities (ARIC) study and is the PI of the coordinating center for the SEARCH for Diabetes in Youth study. She is the overall PI of the GUARDIAN Consortium, a collaboration of 7 cohorts examining the genetics of diabetes traits in Hispanics. She is an active mentor, and regularly teaches the Research Grant Preparation course in the Clinical Population and Translational Science graduate program. Dr. Wagenknecht completed a fellowship in the ELAM (Executive Leadership in Academic Medicine) Program for Women in 2009.